CAFESTOL ACETATE
CAFESTOL ACETATE Basic information
- Product Name:
- CAFESTOL ACETATE
- Synonyms:
-
- CAFESTOL ACETATE
- 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-7-hydroxy-10b-methyl-, 7-acetate,(3bS,5aS,7R,8R,10aR,10bS)-
- CAS:
- 81760-48-7
- MF:
- C22H30O4
- MW:
- 358.47
- Product Categories:
-
- Phase II Enzyme Inducers
- Phase II Enzyme InducersCancer Research
- Cancer Research
- Chemopreventive Agents
- Multidrug Resistance
- Mol File:
- 81760-48-7.mol
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CAFESTOL ACETATE Chemical Properties
- Melting point:
- 163～165℃
- Boiling point:
- 474.6±45.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 14.17±0.40(Predicted)
- form
- powder
- color
- white to off-white
MSDS
- Language:English Provider:SigmaAldrich
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CAFESTOL ACETATE Usage And Synthesis
Uses
Cafestol acetate is a glutathione S-transferase inducer.
Biological Activity
Cafestol is a coffee-specific diterpene. It has anti-carcinogenic and anti-inflammatory activities. Cafestol stimulates apoptosis in cells associated with colorectal and renal cancer (Caki cells). It is used to study mechanisms of anti-oxidation related to hydrogen peroxide induced oxidative stress and DNA damage. Cafestol increases the level of glutathione (GSH), by stimulating γ-glutamylcysteine synthetase. It acts as a chemopreventive agent by inducing cytochrome P-450.
CAFESTOL ACETATESupplier
Energy Chemical
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- 021-58432009 400-005-6266
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Shanghai Yingxin laboratory equipment Co., Ltd
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- 021-021-59178156 15300768757
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Shanghai Guchen Biotechnology Co., LTD
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Hu Bei Jiutian Bio-medical Technology CO.,Ltd
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