4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE Chemical Properties

Melting point:

156.7-157.3 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))

storage temp. 

Desiccate at RT

form 

Powder

Water Solubility 

Soluble to 100 mM in water

4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE Usage And Synthesis

Uses

4-(1H-Imidazol-4-ylmethyl)-1-methylpiperidine Dihydrobromide is a salt analog of methimepip, which exhibits high affinity and agonist activity at the human histamine H3 receptor.

Biological Activity

Extremely selective histamine H 3 receptor agonist (pK i values are 9.0, 5.7, < 5.0 and < 5.0 for hH 3 , hH 4 , hH 1 and hH 2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD 2 = 8.26).

4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE(817636-54-7)Related Product Information

• 4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE
• 4-(1H-IMIDAZOL-4-YL)-BUTYLAMINE 2HBR
• 1-ETHYL-4-(1H-IMIDAZOL-4-YLMETHYL)-PIPERIDINE 2HBR
• 4-(1H-IMIDAZOL-4-YLMETHYL)-1-METHYLPIPERIDINE DIHYDROBROMIDE