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3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one

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3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Basic information

Product Name:
3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one
Synonyms:
  • Risperidone Z-OxiMe IMpurity
  • Risperidone IMpurity B
  • Risperidone EP IMpurity B
  • 3-[2-[4-[(Z)-(2,4-difluorophenyl)(hydroxyimino)methyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
  • (Z)-3-(2-(4-((2,4-difluorophenyl)(hydroxyimino)methyl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
  • Risperidone Impurity 1(Risperidone EP Impurity B)
  • 3-[2-[4-[(Z)-C-(2,4-difluorophenyl)-N-hydroxycarbonimidoyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
  • Risperidone EP Imp B
CAS:
132961-05-8
MF:
C23H28F2N4O2
MW:
430.49
EINECS:
603-689-1
Product Categories:
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Aromatics
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
132961-05-8.mol
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3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Chemical Properties

Boiling point:
569.0±60.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
vapor pressure 
0-0Pa at 20-25℃
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid:particulate/powder
pka
11.20±0.28(Predicted)
LogP
0.6-2.1 at 20℃ and pH6.9-10.4
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3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one Usage And Synthesis

Uses

Risperidone Z-Oxime is an impurity of Risperidone (R525000). Risperidone impurity per USP.

3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-oneSupplier

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3-[2-[4-[(Z)-(2,4-Difluorophenyl)(hydroxyiMino)Methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-Methyl-4H-pyrido[1,2-a]pyriMidin-4-one(132961-05-8)Related Product Information