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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride

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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Basic information

Product Name:
6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride
Synonyms:
  • 4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINE
  • ASINEX-REAG BAS 13549338
  • 6--3-(4-)-1,2 KY-16-05
  • Paliperidone Related CoMpound B
  • 1,2-Benzisoxazole,6-fluoro-3-(4-piperidinyl)-, hydrochloride (1:1)
  • Paliperidone int 2
  • Paliperidone Related Compound B (20 mg) (6-fluoro-3-(piperidin-4-yl)benzoisoxazole hydrochloride)
  • Iloperidone intermediate
CAS:
84163-13-3
MF:
C12H14ClFN2O
MW:
256.7
EINECS:
700-303-4
Product Categories:
  • APIs Intermediate
  • Iloperidone Intermediate
  • Oxazole&Isoxazole
  • (intermediate of risperidone)
Mol File:
84163-13-3.mol
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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Chemical Properties

Melting point:
293-295 °C
Density 
1.42g/cm3 at 20℃
vapor pressure 
0.002-0.005Pa at 20-25℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly, Heated)
form 
Solid
color 
White to Off-White
LogP
-0.84 at 20℃ and pH7
CAS DataBase Reference
84163-13-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2934990002
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6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride Usage And Synthesis

Uses

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Hydrochloride (Risperidone EP Impurity M; Paliperidone USP Related Compound B) is a novel antiproliferative agent.

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