Basic information Safety Supplier Related

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Basic information Safety Supplier Related

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Basic information

Product Name:
8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms:
  • 11-Fluoro Desloratadine
  • 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • Desloratadine EP Impurity A
  • 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo [5,6] cyclohepta [1,2-b]pyridin-11-yl]piperidine
  • 8-chloro-11-fluoro-11-piperidin-4-yl-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
  • Desloratadine Impurity 1/Desloratadine EP Impurity A
  • 11-Fluoro Desloratadine HCl
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-
CAS:
298220-99-2
MF:
C19H20ClFN2
MW:
330.83
Product Categories:
  • Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
298220-99-2.mol
More
Less

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Chemical Properties

Melting point:
>192°C (dec.)
Boiling point:
426.9±45.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
10.16±0.10(Predicted)
form 
Solid
color 
Off-White to Pale Orange
More
Less

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Usage And Synthesis

Uses

11-Fluoro Desloratadine (Desloratadine EP Impurity A) is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

Uses

11-Fluoro Desloratadine is a fluorine substituted benzocycloheptapyridine derivative with antihistaminic activity.

8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridineSupplier

Z-trans Biochemistry Technology (Suzhou) Co.,Ltd Gold
Tel
0512-66317708 13372112871
Email
huijuan@zitrans.cn
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Email
3001272453@qq.com