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ChemicalBook >  Product Catalog >  Analytical Chemistry >  Standard >  Pharmaceutical Impurity Reference Standards >  4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide

4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide

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4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide Basic information

Product Name:
4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide
Synonyms:
  • 4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide
  • N-Desmethoxypropyl Prucalopride
  • Prucalopride intermediate Impurity 3-3
  • Prucalopride intermediate Impurity 3-11
  • Prucalopride Impurity 8/4-amino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-Benzofurancarboxamide
  • Prucalopride N-Desmethoxypropyl Impurity
  • 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-4-piperidinyl-
  • Prucalopride Succinate iMpurit J
CAS:
137211-64-4
MF:
C14H18ClN3O2
MW:
295.76
Mol File:
137211-64-4.mol
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4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide Chemical Properties

Boiling point:
427.6±45.0 °C(Predicted)
Density 
1.36±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.69±0.20(Predicted)
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4-aMino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-BenzofurancarboxaMide Usage And Synthesis

Uses

N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.

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