bortezoMib iMpurity H
bortezoMib iMpurity H Basic information
- Product Name:
- bortezoMib iMpurity H
- Synonyms:
-
- (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
- Bortezomib Imp.H
- Bortezomib Impurity S
- Bortezomib impurity 11/(S)-N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
- 2-Pyrazinecarboxamide, N-[(1S)-2-[(3-methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-
- Bortezomib impurity H
- CAS:
- 1446194-56-4
- MF:
- C19H24N4O2
- MW:
- 340.42
- Mol File:
- 1446194-56-4.mol
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bortezoMib iMpurity H Chemical Properties
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly)
- form
- Solid
- color
- White to Off-White
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bortezoMib iMpurity H Usage And Synthesis
Uses
N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is an impurity of Bortezomib (B675700) which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
bortezoMib iMpurity HSupplier
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