(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties

Melting point:

168-170°C

Boiling point:

619.4±55.0 °C(Predicted)

Density 

1.280±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

pka

11.92±0.46(Predicted)

form 

Solid

color 

White to Off-White

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Usage And Synthesis

Uses

N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.

(S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide(289472-80-6)Related Product Information

• Bortezomib
• bortezoMib iMpurity F
• 2,3-Pyrazinedicarboxylic acid
• Bortezomib Impurity 35
• Bortezomib Impurity 23
• tert-Butyl Tosylate DISCONTINUED
• Bortezomib Impurity 5
• 1-Chloro-2-methylpropane
• Bortezomib Impurity 45
• BOC-D-Phenylalanine
• 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
• ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
• 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]-
• N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
• ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
• N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
• 1-Bromo-2-methylpropane
• Bortezomib Impurity 47 HCl