Basic information Safety Supplier Related

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

Basic information Safety Supplier Related

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Basic information

Product Name:
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
Synonyms:
  • ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
  • Boronic acid, B-[(1S)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
  • (1S,2S)-BortezoMib
  • (1S,2S)-Bortezomib Impurity
  • [(1S)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid
  • Bortezomib Impurity PS619
  • N-(2-Pyrazinecarbonyl)-L-phenylalanine-D-leucine boronic anhydride
  • Bortezomib (1S,2S) Isomer Impurity
CAS:
1132709-14-8
MF:
C19H25BN4O4
MW:
384.24
Product Categories:
  • Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
1132709-14-8.mol
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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Chemical Properties

Density 
1.214±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
form 
Solid
pka
9.66±0.43(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Usage And Synthesis

Uses

(1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.

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