ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > Epigenetics > HDAC inhibitors > Tubastatin-A
Tubastatin-A
Tubastatin-A Basic information
- Product Name:
- Tubastatin-A
- Synonyms:
-
- N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
- N-hydroxy-4-((2-methyl-2,3,4,5-tetrahydro-1H-indeno[1,2-c]pyridin-5-yl)methyl)benzamide
- N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Tubastatin A
- Tubastatin A BASE
- Tubastatin A(free base)
- N-hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide
- N-hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-ylmethyl)benzamide
- N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide
- CAS:
- 1252003-15-8
- MF:
- C20H21N3O2
- MW:
- 335.4
- Product Categories:
-
- Inhibitors
- Mol File:
- 1252003-15-8.mol
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Tubastatin-A Chemical Properties
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- insoluble in EtOH; insoluble in H2O; ≥10.75 mg/mL in DMSO
- form
- solid
- pka
- 8.95±0.10(Predicted)
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Tubastatin-A Usage And Synthesis
Definition
ChEBI: A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminoca bonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
target
HDAC6
Tubastatin-ASupplier
Tianjin Kailiqi Biotechnology Co., Ltd. Gold
- Tel
- 15076683720
- klq@cw-bio.com
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
Guangzhou Isun Pharmaceutical Co., Ltd
- Tel
- 020-39119399 18927568969
- isunpharm@qq.com