(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Basic information
- Product Name:
- (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione
- Synonyms:
-
- 9α-Fluoro-11β-hydroxy-16-β-Methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one
- Clobetasol impurity J (PhEur)
- Clobetasol Related Compound A (USP)
- Clobetasol Propionate EP Impurity J
- Clobetasol Propionate Impurity 10(Clobetasol Propionate EP Impurity J)
- 2-tert-butyl-1'-(7-methyl-3a,7a-dihydro-1H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one
- Clobetasol Propionate USP Related Compound A/(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione
- Clobetasol Propionate USP Related Compound A
- CAS:
- 1486466-31-2
- MF:
- C25H30ClFO4
- MW:
- 448.95
- Mol File:
- 1486466-31-2.mol
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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Chemical Properties
- Melting point:
- >276°C (dec.)
- Boiling point:
- 563.7±50.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated)
- pka
- 12.96±0.70(Predicted)
- color
- White to off-White
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Safety Information
- Hazard Codes
- T
- Risk Statements
- 61-48/20/21-53-62
- Safety Statements
- 53-36/37-45
- WGK Germany
- 3
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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Usage And Synthesis
Uses
(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent.
(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dioneSupplier
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(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione(1486466-31-2)Related Product Information
- Clobetasol
- 21-Chloro-9-fluoro-11β,17-dihydroxy-16α-Methylpregna-1,4-diene-3,20-dione 17-Propionate
- 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate
- BETAMETHASONE 21-PROPIONATE
- (11β)-21-Chloro-9-fluoro-11-hydroxy-16-Methylpregna-1,4,16-triene-3,20-dione
- 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- 9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate
- 9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate