Basic information Safety Supplier Related

Sofosbuvir IMpurity C

Basic information Safety Supplier Related

Sofosbuvir IMpurity C Basic information

Product Name:
Sofosbuvir IMpurity C
Synonyms:
  • Sofosbuvir IMpurity C 1337482-15-1
  • Ofosbuvi rimpurity
  • isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alaninate
  • Sofosbuvir impurity G
  • (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
  • isopropyl ((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)-L-alanite
  • Sofosbuvir 5'-Desphosphate 3’-O-[(S)-Phosphate]
  • sofosbuvir impurity Y008005-G
CAS:
1337482-15-1
MF:
C22H29FN3O9P
MW:
529.45
Mol File:
1337482-15-1.mol
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Sofosbuvir IMpurity C Chemical Properties

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
soluble in No data available
pka
9.39±0.10(Predicted)
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Sofosbuvir IMpurity C Usage And Synthesis

Uses

Sofosbuvir 5''-Desphosphate 3''-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity CSupplier

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