Sofosbuvir IMpurity C Chemical Properties

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

soluble in No data available

pka

9.39±0.10(Predicted)

form 

Solid

color 

White to off-white

Sofosbuvir IMpurity C Usage And Synthesis

Uses

Sofosbuvir 5''-Desphosphate 3''-O-[(S)-Phosphate] is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

Sofosbuvir IMpurity C(1337482-15-1)Related Product Information

• SofosBuvir Impurity 53
• Zolmitriptan
• ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-4-Methyltetrahydrofuran-2-yl)Methyl benzoate
• Cytidine,N-benzoyl-2^-C-Methyl-,3^,5^-dibenzoate(9CI)
• PSI-7977-13C-d3
• SofosBuvir Impurity 40
• 2'-deoxy-2'-fluoro-2'-C-methyluridine
• SofosBuvir Impurity 54
• D-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-uridylyl]-, 1-Methylethyl ester
• Sofosbuvir metabolites GS566500
• sofosBuvir impurity 41
• Sofosbuvir Impurity 7
• Sofosbuvir Impurity25
• Sofosbuvir impurity L
• Sofosbuvir Impurity Q
• sofosBuvir Impurity 35
• Sodium stearyl lactate
• Sofosbuvir