Anti-Protein Wnt-10a precursor Chemical Properties

storage temp. 

-20°C

form 

buffered aqueous solution

biological source

rabbit

Safety Information

WGK Germany 

WGK 1

Storage Class

10 - Combustible liquids

Anti-Protein Wnt-10a precursor Usage And Synthesis

Biological Activity

The protein encoded by the gene WNT10A (wingless-type MMTV integration site family member 10A) may be involved in the inhibition of adipogenesis as its expression is found to be downregulated during the development of white adipocytes. It is found to stabilize β-catenin and stimulate osteoblastogenesis. It regulates the fate of mesenchymal stem cell (MSC). Mutations in this gene has been linked to Odonto-onycho-dermal dysplasia, an autosomal recessive syndrome, characterized by dry hair, severe hypodontia, smooth tongue with marked reduction of fungiform and filiform papillae, onychodysplasia, keratoderma and hyperhidrosis of palms and soles, and hyperkeratosis of the skin.