Histone deacetylase 7 Chemical Properties

storage temp. 

-70°C

form 

buffered aqueous glycerol solution

biological source

human

Specific Activity

64-96RLU/min·ng

Histone deacetylase 7 Usage And Synthesis

Uses

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biological Activity

Histone deacetylases (HDACs) play crucial roles in the epigenetic modulation of gene expression and helps in the growth, differentiation, and apoptosis of cancer cells. Knockdown of HDAC7 stimulates apoptosis and autophagy in salivary mucoepidermoid carcinoma cells. It may play a vital role in both types of B lymphopoiesis. HDAC7 serves as a repressor of myeloid genes.

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