Histone deacetylase 7
Histone deacetylase 7 Basic information
- Product Name:
- Histone deacetylase 7
- Synonyms:
-
- HD7
- HD7A
- HDAC-7 human
- HDAC7A
- Histone deacetylase 7
- DKFZp586J0917
- FLJ99588
- HDAC7, active, GST tagged human
- MW:
- 0
- Mol File:
- Mol File
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Histone deacetylase 7 Chemical Properties
- storage temp.
- -70°C
- form
- buffered aqueous glycerol solution
- biological source
- human
- Specific Activity
- 64-96RLU/min·ng
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Histone deacetylase 7 Usage And Synthesis
Uses
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Biological Activity
Histone deacetylases (HDACs) play crucial roles in the epigenetic modulation of gene expression and helps in the growth, differentiation, and apoptosis of cancer cells. Knockdown of HDAC7 stimulates apoptosis and autophagy in salivary mucoepidermoid carcinoma cells. It may play a vital role in both types of B lymphopoiesis. HDAC7 serves as a repressor of myeloid genes.