(-)-TRAMADOL
(-)-TRAMADOL Basic information
- Product Name:
- (-)-TRAMADOL
- Synonyms:
-
- (-)-2-[(DIMETHYLAMINO)METHYL]-1-(3-METHOXYPHENYL)CYCLOHEXANOL
- Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1S,2R)-
- CAS:
- 181289-59-8
- MF:
- C16H25NO2
- MW:
- 263.38
- Mol File:
- 181289-59-8.mol
More
Less
(-)-TRAMADOL Chemical Properties
- Boiling point:
- 388.1±22.0 °C(Predicted)
- Density
- 1.047±0.06 g/cm3(Predicted)
- pka
- 14.47±0.40(Predicted)
More
Less
(-)-TRAMADOL Usage And Synthesis
Definition
ChEBI: (S,S)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have S-configuration; the (S,S)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold lower analgesic potency than the (R,R)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist and a serotonin uptake inhibitor. It is a conjugate base of a (S,S)-tramadol(1+). It is an enantiomer of a (R,R)-tramadol.