T5601640
T5601640 Basic information
- Product Name:
- T5601640
- Synonyms:
-
- T5601640
- T56-LIMKi
- 3-methyl-N-[3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1,2-oxazole-5-carboxamide
- T-5601640(T56-LIMKi)
- 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide
- T5601640;T 5601640;T56-LIMKI
- T56-LIMKi - T5601640
- 5-Isoxazolecarboxamide, 3-methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-
- CAS:
- 924473-59-6
- MF:
- C19H14F3N3O3
- MW:
- 389.33
- EINECS:
- 604-604-1
- Mol File:
- 924473-59-6.mol
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T5601640 Chemical Properties
- Boiling point:
- 403.4±45.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 20 mg/ml
- form
- powder
- pka
- 11.41±0.70(Predicted)
- color
- white to beige
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T5601640 Usage And Synthesis
Uses
T 5601640 is a LIMK inhibitor and is used for the treatment of proliferative disorders such as cancer, neurofibromatosis and neuronal differentiation associated disaeses.
Biochem/physiol Actions
T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells.
storage
Store at +4°C
T5601640Supplier
Sigma-Aldrich
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Shanghai Lollane Biological Technology Co.,Ltd.
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