8-Bromoquinoline Chemical Properties

Melting point:

58-59 °C

Boiling point:

112-113 °C/0.5 mmHg (lit.)

Density 

1.594 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.672(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,2-8°C

form 

Liquid After Melting

pka

2.33±0.17(Predicted)

Specific Gravity

1.594

color 

Clear yellow to yellow-brown

Sensitive 

Light Sensitive

InChIKey

PIWNKSHCLTZKSZ-UHFFFAOYSA-N

CAS DataBase Reference

16567-18-3(CAS DataBase Reference)

NIST Chemistry Reference

Quinoline, 8-bromo-(16567-18-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29334900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

8-Bromoquinoline Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

8-Bromoquinoline may be used in the following studies:

• Synthesis of 8-(dimesitylboryl)quinolone (ambiphilic molecule).
• Direct synthesis of 5H-pyrido[3,2,1-ij]quinolin-3-one, via palladium catalyzed coupling reaction with acrolein.
• Preparation of 8-(1-hydroxyethyl)quinolone.
• Preparation of 8-quinolylcyclopentadienyl metal complexes, via reaction with zincated cyclopentadienyl derivatives of Fe, Mn and Re in the presence of bis(triphenylphosphine)palladium(0).
• Synthesis of n,n′-biquinolines by a coupling reaction using tris(triphenylphosphine)nickel(0) and a zerovalent pyridine-nickel complex.

General Description

8-Bromoquinoline is a quinolone derivative. It is widely employed for the synthesis of dyes, food colors, pharmaceutical reagents, pH indicators and in various industrial processes. Its molecule bears a pyridyl group. It undergoes direct heteroarylation reaction with various heteroaromatic compounds in the presence of a palladium catalyst to afford polyheteroaromatic derivatives.

8-Bromoquinoline(16567-18-3)Related Product Information

• Ethoxyquin
• Isoquinoline
• Quinolinic acid
• 8-Hydroxyquinoline
• QUINOLINE SULPHATE
• Quinclorac
• Quinhydrone
• 8-BROMOQUINOLINE-4-OL
• 2-BROMOQUINOLINE 98%
• 8-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID
• 8-BROMO-4-CHLOROQUINOLINE
• 8-BROMO-4-CHLORO-2-METHYLQUINOLINE
• 8-BROMO-5-NITROQUINOLINE
• ETHYL 8-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLATE
• 4-Bromoquinoline-3-boronic acid, 97%
• 4-bromoquinoline-6-carboxylic acid
• 4-Amino-3-bromoquinoline
• 8-BROMO-4-HYDROXY-2-METHYLQUINOLINE