1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Chemical Properties

Boiling point:

482.3±45.0 °C(Predicted)

Density 

1.46±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

pka

13.27±0.20(Predicted)

1,4-Benzodioxin-5-carboxamide, 8-amino-7-chloro-N-[(2S)-1,4-diazabicyclo[2.2.2]oct-2-ylmethyl]-2,3-dihydro- Usage And Synthesis

Uses

5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows 5-HT3 inhibition activity.

IC 50

5-HT₃ Receptor

References

[1] Jegham S, et al. Derivatives of N-(1,4-diazabicyclo(2.2.2)-oct-2-yl)methyl benzamide, their preparation and their therapeutical use. EP0748807A1.