TCO-PNB Ester Chemical Properties

Boiling point:

433.9±45.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

storage temp. 

-20°C

form 

powder or chunks

color 

Off-white to light yellow

TCO-PNB Ester Usage And Synthesis

Description

TCO-PNB Ester contains two reactive substituents. The PNB ester is reactive with amine groups. TCO group can participate in Click Chemistry reactions with tetrazine and can be used to label antibodies and proteins.

Uses

TCO-PNB ester (trans-Cyclooctene-p-nitrobenzyl ester) has a p-nitrobenzyl (PNB) ester group that is amine reactive and a trans-cyclooctene (TCO) group that is reactive with tetrazines. TCO-PNB ester is supplied as a single axial (major) diastereomer. This specially formulated crystalline material provides easy handling and extended shelf life.

TCO-PNB Ester(1438415-89-4)Related Product Information

• TCO*-PEG3-Maleimide
• TCO*-PEG7-Maleimide
• TCO*-PEG3-COOH
• TCO*-PEG3-NH2
• TCO*-PEG8-NHS
• TCO*-PEG3-NHS
• TCO*-PEG4-COOH
• TCO*-PEG2-NH2
• TCO*-PEG4-NHS
• TCO*-PEG8-COOH
• TCO*-PEG2-Maleimide
• TCO-carbonate
• TCO*-PEG7-NH2
• TCO/E- active ester (p-NPE) / equatorial