4-BENZYLOXYBUTYRIC ACID Chemical Properties

Boiling point:

135 °C/0.3 mmHg (lit.)

Density 

1.097 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.512(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

pka

4.63±0.10(Predicted)

form 

Oil

color 

Colourless to Pale Yellow

InChIKey

CXEFZVVLTJQWBF-UHFFFAOYSA-N

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-27-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

4-BENZYLOXYBUTYRIC ACID Usage And Synthesis

Uses

4-Benzyloxybutyric acid may be used in the synthesis of benzyloxybutyryl (BOB) esters of alcohols by standard acylation techniques or by the Jacobsen asymmetric nucleophilic ring opening of epoxides.

Synthesis Reference(s)

Tetrahedron, 53, p. 8853, 1997 DOI: 10.1016/S0040-4020(97)90396-3

General Description

4-Benzyloxybutyric acid can be synthesized from γ-butyrolactone. It participates in the asymmetric total synthesis of erythromycin.

4-BENZYLOXYBUTYRIC ACID(10385-30-5)Related Product Information

• Boc-D-aspartic acid 4-benzyl ester
• N-Cbz-L-Aspartic acid 4-benzyl ester
• Z-ASP-OBZL
• DIBENZYL SUCCINATE
• L-Aspartic acid dibenzyl ester 4-toluenesulfonate
• L-Aspartic acid 4-benzyl ester
• D-ASPARTIC ACID(OBZL)-OBZL P-TOSYLATE
• BOC-ASP(OBZL)-OSU
• Reserpine
• SYROSINGOPINE
• L-Aspartic acid benzyl ester
• CBZ-ASP(OBZL)-OBZL
• BOC-HYP(BZL)-OH
• H-D-ASP-OBZL
• Boc-L-aspartic acid 1-benzyl ester
• Boc-L-aspartic acid 4-benzyl ester
• BOC-D-ASP(OBZL)-OH
• Z-L-ASPARTIC ACID 4-BENZYL 1-(4-NITROPHENYL) ESTER