L-3,5-DIFLUOROPHE Chemical Properties

Boiling point:

295.1±40.0 °C(Predicted)

Density 

1.379±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Methanol (Slightly), Water (Slightly)

form 

Solid

pka

2.13±0.20(Predicted)

color 

White to Off-White

InChI

InChI=1S/C9H9F2NO2/c10-6-1-5(2-7(11)4-6)3-8(12)9(13)14/h1-2,4,8H,3,12H2,(H,13,14)/t8-/m0/s1

InChIKey

QFGMPXZFCIHYIR-QMMMGPOBSA-N

SMILES

C(O)(=O)[C@H](CC1=CC(F)=CC(F)=C1)N

CAS DataBase Reference

31105-91-6(CAS DataBase Reference)

Safety Information

HS Code 

2922498590

L-3,5-DIFLUOROPHE Usage And Synthesis

Chemical Properties

Cream colored powder

Uses

H-Phe(3,5-DiF)-OH is a difluorophenylalanines in the L-configuration [L-(F2)Phe]. H-Phe(3,5-DiF)-OH can be incorporated into the thrombin receptor-tethered ligand peptide SFLLRNP to identify the phenyl hydrogens of the Phe-2 residue involved in the CH/π receptor interaction[1].

References

[1] Fujita T, et al. Synthesis of a complete set of l-difluorophenylalanines, l-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor. Tetrahedron Letters. 2000, 41(6):923-927.

L-3,5-DIFLUOROPHE(31105-91-6)Related Product Information

• L-3,4-DIFLUOROPHE
• 3,3-Diphenyl-L-alanine
• 3,4-Dichlorophenylalanine
• DL-3,4-Difluorophenylalanine
• 2,4-Difluoro-D-phenylalanine
• 2,5-DIFLUORO-DL-PHENYLALANINE
• FMOC-D-3,5-DIFLUOROPHE
• BOC-L-3,5-DIFLUOROPHE
• BOC-L-3,4-DIFLUOROPHE
• FMOC-L-3,4-DIFLUOROPHE
• FMOC-D-3,4-DIFLUOROPHE
• 2,5-Difluoro-D-phenylalanine
• BOC-D-3,4-DIFLUOROPHE
• (S)-2-AMINO-3-(2,3-DIFLUORO-PHENYL)-PROPIONIC ACID
• 2,3-Difluoro-D-phenylalanine
• DL-3,5-DIFLUOROPHENYLALANINE
• 3,5-Difluoro-D-phenylalanine
• 3,4-Difluoro-D-phenylalanine