LITHIUM SALICYLATE Chemical Properties

Melting point:

>350 °C (lit.)

Density 

1.428[at 20℃]

form 

Powder

Water Solubility 

Soluble in water

BRN 

3732791

CAS DataBase Reference

552-38-5(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 2-hydroxy-, monolithium salt (552-38-5)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/38

Safety Statements 

22-26-36

WGK Germany 

1

F 

3-10

TSCA 

Yes

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

LITHIUM SALICYLATE Usage And Synthesis

Description

Lithium salicylate is the lithium salt of salicylate, which is a kind of organic acid. Lithium salicylate may be a good alternative for treating bipolar disorder and other neuropsychiatric conditions as it was recently found that oral lithium salicylate was able to produce steady lithium levels for up to 48 hours in rats – without the toxic side effects typically linked with the rapid absorption of current FDA-approved lithium carbonate. It is also proposed that lithium salicylate is most effective drug in reducing self-harm and suicide.
The therapeutic effect of lithium salicylate allows for its application in diuretics. In addition, with the aid of its catalysis effect, this chemical can be employed as the catalysts for chemiluminescent system or trimer catalyst for aliphatic and aromatic isocyanates.

Sources

https://www.redorbit.com/news/health/1113093183/biploar-disorder-lithium-therapy-sodium-based-better-031214/
https://www.theguardian.com/society/2016/aug/14/lithium-should-be-more-widely-used-for-bipolar-disorder-researchers-say
https://www.sdrugs.com/?c=drug&s=lithium%20salicylate
Junquera, E.; Pena, L.; Aicart, E., Binding of sodium salicylate by beta-cyclodextrin or 2,6-di-O-methyl-beta-cyclodextrin in aqueous solution. J. Pharm. Sci. 1998, 87, 86-90.
Herbert, P. R.; Joseph, H. J., Chemiluminescent system catalysts. United Sates Patent 4626383 1986.
W.E., S.; H.T., K.; T., H., Trimer catalyst for aliphatic and aromatic isocyanates. United Sates Patent 5905151 1999.

Flammability and Explosibility

Not classified

Purification Methods

Recrystallise it from EtOH (2mL/g) by partial evaporation. [Beilstein 10 H 59, 10 II 32, 10 III 93, 10 IV 126.]

LITHIUM SALICYLATE(552-38-5)Related Product Information

• N-Methylpropionamide
• 3-Methylsalicylic acid
• Methyl salicylate
• BISMUTH SUBSALICYLATE
• Salicylic acid
• Lithium
• Lithium benzoate
• LITHIUM 3,5-DIIODOSALICYLATE
• 2,5-DIHYDROXYBENZOIC ACID LITHIUM SALT
• LITHIONCARMINE
• LITHIUMCARMINE
• ACETYLSALICYLIC ACID, LITHIUM SALT
• 3,5-DIIODOSALICYLIC ACID LITHIUM SALT MONOHYDRATE
• LITHIUM 3,5-DIIODOSALICYLATE
• LITHIUM SALICYLATE