SOLANIDINE
SOLANIDINE Basic information
- Product Name:
- SOLANIDINE
- Synonyms:
-
- SOLATUBINE
- SOLANIDINE
- SOLANIDINE HCL
- (3-beta)-solanid-5-en-3-o
- 22R,25S-Solanidanine
- 3-beta-Solanid-5-en-3-ol
- solanid-5-en-3-beta-ol
- Solanid-5-en-3beta-ol
- CAS:
- 80-78-4
- MF:
- C27H43NO
- MW:
- 397.64
- EINECS:
- 201-309-5
- Product Categories:
-
- Alkaloids
- Mol File:
- 80-78-4.mol
SOLANIDINE Chemical Properties
- Melting point:
- 212-214°C
- alpha
- D21 -29° (c = 0.5 in chloroform)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated)
- form
- Solid
- color
- White to Off-White
- LogP
- 7.100 (est)
Safety Information
- Hazard Codes
- T+,Xn
- Risk Statements
- 23/24/25-53-22
- Safety Statements
- 2-13-45-36/37/39-22
- RIDADR
- 1544
- WGK Germany
- 3
- RTECS
- WF0500000
- HazardClass
- 6.1(b)
- PackingGroup
- III
SOLANIDINE Usage And Synthesis
Uses
Soladine has been shown to display mutagenic properties in the liver, and is stored in the body for prolonged periods of time.
Definition
ChEBI: Solanidine is a steroid alkaloid fundamental parent, a 3beta-hydroxy-Delta(5)-steroid and a solanid-5-en-3-ol. It has a role as a plant metabolite and a toxin. It is a conjugate base of a solanidine(1+).
Purification Methods
Solanidine crystallises from CHCl3/MeOH, aqueous EtOH or aqueous MeOH as needles. TLC on Al2O3 plates using CH2Cl2/MeOH (98:2) gives a spot at RF 0.47. The hydrochloride crystallises from aqueous EtOH with m 345o(dec). The acetate crystallises from EtOH with m 208o. [Schreiber & Roensch Tetrahedron 21 6451965, Kessar et al. Tetrahedron 27 2153 1971, Reichestein & Reich Ann Rev Biochem 15 155 1946, Beilstein 21 III/IV 1398, 27 III/IV 2000.]
SOLANIDINESupplier
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