BENZYLOXYTRIMETHYLSILANE Chemical Properties

Boiling point:

92 °C

Density 

0.916

refractive index 

1.4770

Flash point:

73°C

solubility 

Chloroform, Dichloromethane

form 

Yellow Liquid

color 

Colorless to Light yellow to Light red

Specific Gravity

0.916

Hydrolytic Sensitivity

7: reacts slowly with moisture/water

NIST Chemistry Reference

Silane, trimethyl(phenylmethoxy)-(14642-79-6)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-24/25-23

TSCA 

No

HS Code 

29310099

BENZYLOXYTRIMETHYLSILANE Usage And Synthesis

Chemical Properties

Clear very pale yellow liquid

Uses

Benzyloxytrimethylsilane is an intermediate in the synthesis of [Di(benzyloxy)methyl]benzene (D417965), which is a reagent in organic chemical synthesis such as the synthesis of O-benzyl protected anti aldols.

Definition

ChEBI: Benzyl trimethylsilyl ether is a silyl ether that is benzyl alcohol in which the hydroxyl hydrogen is replaced by a trimethylsilyl group. It is a silyl ether and a member of benzenes. It is functionally related to a benzyl alcohol.

Synthesis

Benzyloxytrimethylsilane was prepared as follows: benzyl alcohol (1 mmol) was added to a mixture of HMDS (1 mmol) and MNPs-DABCO tribromide (10 mg) under solvent-free conditions, and then the mixture was stirred at room temperature for the specified time. The progress was monitored by TLC. Upon completion of the reaction, the catalyst was separated from the product (within 5 s) and washed with Et2O (2 ?? 5 mL). 10% aqueous NaHCO3 (3 mL) was added to destroy the additional amount of HMDS, then the organic layer was separated and dried with anhydrous Na2SO4. Evaporation under Et2O under reduced pressure allowed pure TMS-ether to be obtained without additional purification to give benzyloxytrimethylsilane.

BENZYLOXYTRIMETHYLSILANE(14642-79-6)Related Product Information

• N-Carbobenzyloxy-L-alanine
• BENZYLOXYTRIMETHYLSILANE
• 1,2-BIS(TRIMETHYLSILOXYMETHYL)BENZENE
• 1-PHENYL-1-TRIMETHYLSILOXYETHYLENE
• TRIMETHYLSILANE
• 2-[4-(TERT-BUTYLDIMETHYLSILYLOXYMETHYL)-2-NITROPHENOXY]ACETIC ACID
• (4-BROMOPHENYL)METHOXY-TERT-BUTYL-DIMETHYLSILANE
• [4-[[[1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]phenylboronic Acid
• (M,P-VINYLBENZYLOXY)TRIMETHYLSILANE
• ALPHA-(TRIMETHYLSILYLOXY)PHENYLACETONIT&
• [4-(TERT-BUTYL-DIMETHYL-SILANYLOXYMETHYL)PHENYL]-ACETIC ACID
• 3-(2-BROMO-PHENYL)-2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PROPIONIC ACID
• 2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-3-NAPHTHALEN-1-YL-PROPIONIC ACID
• (3,4-DIHYDRO-1-NAPHTHYLOXY)TRIMETHYLSILANE
• 2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
• 2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-3-(2-METHOXY-PHENYL)-PROPIONIC ACID
• 2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-3-(3-PHENOXY-PHENYL)-PROPIONIC ACID
• 3-(4-BROMO-PHENYL)-2-TERT-BUTOXYCARBONYLAMINO-3-(TERT-BUTYL-DIMETHYL-SILANYLOXY)-PROPIONIC ACID