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ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT

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ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Basic information

Product Name:
ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT
Synonyms:
  • ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT
  • ATP MAGNESIUM SALT
  • ATP-MG
  • adenosine 5'-triphosphate magnesium*from equine M
  • ADENOSINE 5'-TRIPHOSPHATE MAGNESIUMFROM BACTERIAL
  • ATP MAGNESIUM
  • adenosine 5'-triphosphate magnesium salt trihydrate
  • Adenosine 5′-triphosphate magnesium salt,ATP magnesium salt
CAS:
74804-12-9
MF:
C10H18MgN5O13P3
MW:
533.5
Mol File:
74804-12-9.mol
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ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Chemical Properties

Melting point:
>300°C
storage temp. 
-20°C
solubility 
H2O: 50 mg/mL
form 
Solid
color 
White to Pale Yellow
biological source
bacterial
Water Solubility 
H2O: 50mg/mL
Stability:
Hygroscopic
InChIKey
CPGAIACWYFBIFN-UHFFFAOYSA-N
SMILES
[Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-68/20/21/22
Safety Statements 
36/37
WGK Germany 
1
Storage Class
11 - Combustible Solids
Hazard Classifications
STOT SE 2

MSDS

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ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALT Usage And Synthesis

Uses

Adenosine 5′-triphosphate magnesium salt has been used:

  • as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
  • as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
  • as a component in action potential intracellular solution

Biochem/physiol Actions

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

in vivo

ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo[4].
ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo[4].

Animal Model:Four-week-old Kunming mice (18-22 g)[4]
Dosage:50 mg/kg
Administration:Intraperitoneal injection, before bacterial (E. coli) challenge
Result:Protected mice from bacterial infection.

IC 50

Human Endogenous Metabolite

ADENOSINE 5'-TRIPHOSPHATE MAGNESIUM SALTSupplier

Hubei wei shi reagent group ltd., company Gold
Tel
027-59105166; 13125137732
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2853863890@qq.com
Bide Pharmatech Ltd.
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400-400-164-7117 18317119277
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product02@bidepharm.com
Shanghai Macklin Biochemical Co.,Ltd.
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15221275939
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shenlinxing@macklin.cn
Sigma-Aldrich
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021-61415566 800-8193336
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orderCN@merckgroup.com
Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
Email
3008007409@qq.com