3-Chlorophenylboronic acid Chemical Properties

Melting point:

185-189 °C(lit.)

Boiling point:

311.4±44.0 °C(Predicted)

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

soluble in Methanol

pka

7.55±0.10(Predicted)

form 

Crystalline Powder or Needles

color 

White to light yellow-green

Water Solubility 

Slightly soluble in water. soluble in ether, tetrahydrofuran,, dimethyl sulfoxide, dimethyl formamide, methanol.

BRN 

2936343

InChI

InChI=1S/C6H6BClO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H

InChIKey

SDEAGACSNFSZCU-UHFFFAOYSA-N

SMILES

B(C1=CC=CC(Cl)=C1)(O)O

CAS DataBase Reference

63503-60-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

36-37/39-26

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Chlorophenylboronic acid Usage And Synthesis

Chemical Properties

white to light yellow-green crystalline powder or

Uses

suzuki reaction

Uses

It is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.

Uses

Reactant involved in:

• 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides
• Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene
• Cross-coupling reactions with diazoesters or potassium cyanate
• Synthesis of biarylketones and phthalides
• Synthesis of inhibitors including PDE4 inhibitors among others

3-Chlorophenylboronic acid(63503-60-6)Related Product Information

• Zinc borate
• 1-Chloro-3-nitrobenzene
• 1,3-Dichlorobenzene
• Phenylboronic acid
• Citric acid
• Chlorphenamine maleate
• Hyaluronic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Folic acid
• Ascoric Acid
• 3,5-Dichlorophenylboronic acid
• 2,3,4-Trichlorophenylboronic acid
• 4-FLUORO-3-CHLOROPHENYLBORONIC ACID
• 2,3-Dichlorophenylboronic acid
• (3,4,5-Trichlorophenyl)boronic acid
• 3,4-Dichlorophenylboronic acid
• 5-CHLORO-2-METHYLPHENYLBORONIC ACID
• 5-CHLORO-2-ETHOXYPHENYLBORONIC ACID