(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Chemical Properties

storage temp. 

protect from light

solubility 

H2O: >10mg/mL at ±60°C (with sonication)

form 

solid

color 

white to off-white

optical activity

[α]25/D +68.2°, c = 1 in methanol(lit.)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-26-36

WGK Germany 

3

(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Usage And Synthesis

Uses

(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:

• in mice to test the activity of the serotonin receptor
• to test its effect on zebrafish melanocyte migration and survival
• to stimulate hippocampal neurons

Biochem/physiol Actions

(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.

storage

Desiccate at +4°C

(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE(78095-19-9)Related Product Information

• 8-HYDROXY-DPAT HYDROBROMIDE
• 2-(2-aminopropyl)phenol
• 8-OH-DPAT·hydrobromide
• (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE
• (R)-2-AMINOTETRALIN
• (R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE
• O-desmethylmethoxyphenamine