Basic information Safety Supplier Related

(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE

Basic information Safety Supplier Related

(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Basic information

Product Name:
(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE
Synonyms:
  • R(+)-8-HYDROXY-DPAT HYDROBROMIDE FULL 5- HT1A SEROTONIN
  • (R)-(+)-2-Dipropylamino-8-hydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide, (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide
  • (R)-(+)-8-Hydroxy-2-(dipropylamino)tetralin hydrobromide
  • Hydroxy-DPAT hydrobromide, (R)-(+)-8-
  • (R) (+) 8 Hydroxy DPAT hydrobromide,(R)(+)8HydroxyDPAT hydrobromide
CAS:
78095-19-9
MF:
C16H25NO.BrH
MW:
328.291
Mol File:
78095-19-9.mol
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(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Chemical Properties

storage temp. 
protect from light
solubility 
H2O: >10mg/mL at ±60°C (with sonication)
form 
solid
color 
white to off-white
optical activity
[α]25/D +68.2°, c = 1 in methanol(lit.)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3
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(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDE Usage And Synthesis

Uses

(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:

  • in mice to test the activity of the serotonin receptor
  • to test its effect on zebrafish melanocyte migration and survival
  • to stimulate hippocampal neurons

Biochem/physiol Actions

(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.

storage

Desiccate at +4°C

(R)-(+)-8-HYDROXY-DPAT HYDROBROMIDESupplier

Sigma-Aldrich
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