L-KYNURENINE SULFATE Chemical Properties

Melting point:

196 °C (decomp)

storage temp. 

−20°C

form 

crystalline

color 

light yellow

Safety Information

WGK Germany 

3

HS Code 

2922500090

L-KYNURENINE SULFATE Usage And Synthesis

Uses

L-Kynurenine Sulfate is a tryptophan metabolite which is a precursor of kynurenic acid (K660500) and an antagonist of N-methyl-aspartate receptor.

Biological Activity

L-Kynurenine (L-Kyn) is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mammals, it modulates the transmission of glutamate neurotransmitter. It is also considered to be a sex-attracting pheromone in vertebrates.', 'L-Kynurenine is a key intermediate in the breakdown of L-tryptophan and the formation of nicotinamide adenine dinucleotide (NAD+) via the kynurenine pathway. L-kynurenine is involved in a variety of neurological processes and diseases. L-kynurenine is a substrate for kynureninase/kynurenine hydrolase; kynurenine 3-monooxygenase and kynurenine-oxoglutarate transaminase.', 'Key intermediate in the breakdown pathway of tryptophan.

Purification Methods

Crystallise the sulfate from water by addition of EtOH. The (±)-sulfate has m 173o. [Beilstein 14 IV 2562.]

L-KYNURENINE SULFATE(16055-80-4)Related Product Information

• DL-KYNURENINE
• L-KYNURENINE
• L-KYNURENINE SULFATE