DL-KYNURENINE Chemical Properties

Melting point:

~235 °C (dec.)

Boiling point:

347.41°C (rough estimate)

Density 

1.343±0.06 g/cm3 (20 ºC 760 Torr)

refractive index 

1.4830 (estimate)

storage temp. 

2-8°C

solubility 

Aqueous Acid (Slightly), Water (Slightly, Heated, Sonicated)

form 

Solid

pka

2.21±0.23(Predicted)

color 

Pale Yellow to Light Yellow

Merck 

13,5343

BRN 

2697333

CAS DataBase Reference

343-65-7(CAS DataBase Reference)

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

DL-KYNURENINE Usage And Synthesis

Uses

vasodilator, immunomodulator

Uses

A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.

Definition

ChEBI: A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Purification Methods

Crystallise it from H2O or aqueous AcOH. The picrate has m 188.5-189o(dec) after crystallisation from H2O. (±)-Kynurenine has m 218o. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p2726 1961, Beilstein 14 III 1657, 14 IV 2562.]

DL-KYNURENINE(343-65-7)Related Product Information

• D-KYNURENINE
• 5-(1H-Indol-3-ylmethyl)imidazolidine-2,4-dione
• Methyl L-tryptophanate hydrochloride
• Tryptophan Impurity 3
• 2,4-Imidazolidinedione, 5-(1H-indol-3-ylmethyl)-, (5R)-
• Tryptophan Impurity 3
• 2-(4-hydroxy-1H-indol-3-yl)acetic acid
• L-KYNURENINE SULFATE
• HYDROXY-DL-KYNURENINE, 3-,3-HYDROXY-DL-KYNURENINE
• dl-kynurenine sulfate,DL-KYNURENINE SULFATE (SALT) MONOHYDRATE,DL-KYNURENINE SULFATE SALT
• Daptomycin
• DL-KYNURENINE
• L-KYNURENINE
• DL-Alanine
• 2-amino-4-(2-amino-3-hydroxy-phenyl)-4-oxo-butanoic acid
• DI-FMOC-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID
• 3-HYDROXYKYNURENINE-O-B-GLUCOSIDE
• D-3-Hydroxykynurenine