(R)-(+)-AMINOGLUTETHIMIDE 97
(R)-(+)-AMINOGLUTETHIMIDE 97 Basic information
- Product Name:
- (R)-(+)-AMINOGLUTETHIMIDE 97
- Synonyms:
-
- (R)-3-(4-aMinophenyl)-3-ethylpiperidine-2,6-dione
- (R)-(+)-Aminoglutethimide 97%
- (R)-(+)-AMINOGLUTETHIMIDE 97
- (R)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
- CGS-2396
- 2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3R)-
- Aminoglutethimide, D-
- (3R)-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione
- CAS:
- 55511-44-9
- MF:
- C13H16N2O2
- MW:
- 232.28
- Product Categories:
-
- Chiral Building Blocks
- Cyclic Imides
- Organic Building Blocks
- Mol File:
- 55511-44-9.mol
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(R)-(+)-AMINOGLUTETHIMIDE 97 Chemical Properties
- Melting point:
- 115.5-119.5 °C (lit.)
- Boiling point:
- 457.4±45.0 °C(Predicted)
- Density
- 1.173±0.06 g/cm3(Predicted)
- pka
- 11.60±0.40(Predicted)
- form
- Solid
- color
- Off-white to light yellow
- optical activity
- [α]20/D +160°, c = 1 in methanol
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(R)-(+)-AMINOGLUTETHIMIDE 97 Usage And Synthesis
Uses
(R)-(+)-Aminoglutethimide can be used:
- As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
- To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
- To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.
Definition
ChEBI: The (3R)-enantiomer of aminoglutethimide.
(R)-(+)-AMINOGLUTETHIMIDE 97Supplier
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Sigma-Aldrich
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