LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Basic information
- Product Name:
- LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)
- Synonyms:
-
- 2,5-dihydroxy-l-tyrosine
- 4,5-trihydroxyphenyl)-3-(l-alanin
- 6-oh-dopa
- l-2,4,5-trihydroxyphenylalanine
- l-6-hydroxydopa
- 3-(3,4,6-Tirhydroxyphenyl)-alanine
- (2S)-2-Amino-3-(2,4,5-trihydroxyphenyl)propanoic acid
- l-hydroxydopa
- CAS:
- 27244-64-0
- MF:
- C9H11NO5
- MW:
- 213.19
- Product Categories:
-
- Amino Acids & Derivatives, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 27244-64-0.mol
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Chemical Properties
- Melting point:
- >190°C (dec.)
- Boiling point:
- 515.2±38.0 °C(Predicted)
- Density
- 1.606±0.06 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated)
- pka
- 2.34±0.25(Predicted)
- color
- Brown to Black
- Stability:
- Air Sensitive, Hygroscopic
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE) Usage And Synthesis
Uses
6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
Uses
6-Hydroxy-L-DOPA is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase.
Definition
ChEBI: An L-alpha-amino acid that is L-dopa carrying an additional hydroxy substituent at position 6.
LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)Supplier
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LEVODOPA RELATED COMPOUND A (50 MG) (3-(3,4,6-TRIHYDROXYPHENYL)-ALANINE)(27244-64-0)Related Product Information
- N,N-DIMETHYL-L-PHENYLALANINE
- 3-(3,4-DIHYDROXYPHENYL-2,5,6-D3)-L-ALANINE
- Albuterol Aldehyde
- Levalbuterol Related Compound B (20 mg) (alpha-[{(1,1-Dimethylethyl)amino}methyl]-4-hydroxy-3-methyl-benzenemethanol)
- 3-O-Methylcarbidopa
- 3,4-dihydroxyphenylacetone
- 2,3-Dihydroxy-DL-Phenylalanine
- 2,3-Dihydroxy-L-Phenylalanine
- 5,6-dihydroxy-1H-indole-2-carboxylic acid
- L-DOPA-4'-Sulfate
- 3-METHOXY-L-TYROSINE
- 3,4-Dimethoxy-L-phenylalanine
- 3-METHOXY-DL-TYROSINE
- L-Tyrosine
- D-DOPA
- Levosimendan Impurity 14
- (S)-3(2h)-Pyridazinone, 6-(4-Aminophenyl)-4,5-Dihydro-5-Methyl-
- Levodopa