1-CHLOROMETHYLPYRENE Chemical Properties

Melting point:

144-145 °C

Boiling point:

434.1±14.0 °C(Predicted)

Density 

1.321±0.06 g/cm3(Predicted)

storage temp. 

<0°C

form 

powder to crystal

color 

White to Orange to Green

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36

RTECS 

UR2450700

HS Code 

2902.90.9000

1-CHLOROMETHYLPYRENE Usage And Synthesis

Uses

1-Chloromethylpyrene is an alkylating agent that enters the DNA double helix structure through intercalation, forms covalent bonds with electrophilic groups, resulting in DNA cross-linking, thereby inhibiting the proliferation of tumor cells[1].

References

[1] Peck RM, et al., Mixed bifunctionality. 4. Antitumor activity of alkylating derivatives of polycyclic aromatic hydrocarbons as a function of structure and of vehicle. J Med Chem. 1972 Jan;15(1):68-70. DOI:10.1021/jm00271a018

1-CHLOROMETHYLPYRENE(1086-00-6)Related Product Information

• 1-Aminopyrene
• Pyrene
• 1-Chloromethyl naphthalene
• 6-CHLOROMETHYLBENZO(A)PYRENE
• 2-(CHLOROMETHYL)NAPHTHALENE
• 1-CHLOROMETHYLPYRENE