METHACETIN-METHOXY-13C Chemical Properties

Melting point:

128-130 °C(lit.)

storage temp. 

Refrigerator

solubility 

Acetone, Alcohol, Chloroform (Sparingly), Methanol (Slightly)

form 

Powder

color 

Crystalline

Stability:

Light and moisture sensitive

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

WGK Germany 

3

RTECS 

AE8290000

HS Code 

28459000

MSDS

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METHACETIN-METHOXY-13C Usage And Synthesis

Chemical Properties

METHACETIN-METHOXY-13C is Crystalline Powder

Uses

METHACETIN-METHOXY-13C is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.

Uses

Labelled Methacetin (M258772) is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.

Definition

ChEBI: Methacetin-(methoxy-(13)C) is a (13)C-modified compound that is methacetin which has (13)C as the predominant isotope of the methoxy carbon. In normal subjects, methacetin is rapidly metabolised in the liver, being dealkylated by hepatic CYP1A2 to give paracetamol (acetaminophen); the methyl of the methoxy group is eliminated as CO2. Administering methacetin-(methoxy-(13)C) to a patient enables the liver (cytochrome P-450 1A2) function to be determined quickly and precisely by measuring the (13)CO2 in the breath (e.g. by isotope-selective non-dispersive infrared spectrometry (NDIRS)). It has a role as an isotopic tracer and a diagnostic agent. It is a (13)C-modified compound, a member of acetamides and an aromatic ether.

METHACETIN-METHOXY-13C(72156-70-8)Related Product Information

• METHACETIN (METHOXY-13C, 99%)
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• METHACETIN-METHOXY-13C