GLUTATHIONE-AGAROSE
GLUTATHIONE-AGAROSE Basic information
- Product Name:
- GLUTATHIONE-AGAROSE
- Synonyms:
-
- GLUTATHIONE-SUPERFLOW RESIN
- GLUTATHIONE-UNIFLOW RESIN
- GLUTATHIONE RESIN
- GLUTATHIONE-AGAROSE
- GLUTATHIONE-AGAROSE BEADS
- GLUTATHIONE AGAROSE, LINKED THROUGH SULFUR
- GSH-AGAROSE
- GSH-agarose, S-linked glutathione agarose
- MW:
- 0
- Mol File:
- Mol File
GLUTATHIONE-AGAROSE Chemical Properties
- Flash point:
- 44 °C
- storage temp.
- 2-8°C
- form
- lyophilized powder
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 10-36/37/38
- Safety Statements
- 16-26-36
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
GLUTATHIONE-AGAROSE Usage And Synthesis
Uses
Useful for affinity capture, molecular pull-down, or immunoprecipitation (IP) of proteins containing glutathione binding sequences, such as recombinant GST-tagged fusion proteins or native glutathione S-transferase, glutathione peroxidase and glyoxalase I from cell lysates and other biological samples. Can be used for purification in single tubes or for high throughput in 96-well multiwell plates. The magnetic properties of the beads aid in manipulations, such as repetitive washings and recovery of the protein. This leads to greater experimental reproducibility and more accurate quantitation of the proteins of interest.
Biological Activity
Glutathione S-transferases (GSTs), a superfamily of multifunctional detoxification isoenzymes, have a significant role in cellular signaling. GSTs are emerging as promising therapeutic targets due to the overexpression of specific isozymes in various tumors and their potential involvement in the development of other diseases such as neurodegenerative diseases, multiple sclerosis, and asthma.