Basic information Safety Supplier Related

alpha-Hydroxybenzenepropanoic acid methyl ester

Basic information Safety Supplier Related

alpha-Hydroxybenzenepropanoic acid methyl ester Basic information

Product Name:
alpha-Hydroxybenzenepropanoic acid methyl ester
Synonyms:
  • (S)-2-HYDROXY-3-PHENYL-PROPIONIC ACID-METHYL ESTER
  • (S)-3-PHENYLLACTIC ACID, METHYL ESTER
  • l-3-phenyl-lactic acid methyl ester
  • L(-) PHENYLLACTIC ACID METHYL ESTER
  • L-METHYL 3-PHENYLLACTATE
  • L-METHYL-BETA-PHENYLLACTATE
  • METHYL L-3-PHENYLLACTATE
  • METHYL (S)-2-HYDROXY-3-PHENYLPROPIONATE
CAS:
13673-95-5
MF:
C10H12O3
MW:
180.2
Product Categories:
  • chiral
Mol File:
13673-95-5.mol
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alpha-Hydroxybenzenepropanoic acid methyl ester Chemical Properties

Melting point:
40-45 °C (lit.)
alpha 
-20.0 º(c=2,H2O)
Boiling point:
110-115 °C(Press: 3 Torr)
Density 
1.150
Flash point:
120°C
storage temp. 
Sealed in dry,Room Temperature
pka
13.00±0.20(Predicted)
optical activity
[α]/D +4.4±0.5°, c = 1% in methanol
CAS DataBase Reference
13673-95-5(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29181990

MSDS

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alpha-Hydroxybenzenepropanoic acid methyl ester Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

Methyl?L-3-phenyllactate can be used:

  • As an intermediate in the synthesis of bortezomib analogs as 20S proteasome inhibitors.
  • As a substrate in the amination of the benzylic C-H bonds and the aminated products are further used to prepare β-lactams.
  • As an intermediate in one of the key synthetic steps for the preparation of YM-254890 analog, a selective Gαq/11 inhibitor.

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