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Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate

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Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate Basic information

Product Name:
Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate
Synonyms:
  • METHYL TRANS-3-(4-METHOXYPHENYL)GLYCIDATE
  • 3-(4-methoxyphenyl)-oxiranecarboxylicacimethylester
  • 3-(-methoxyphenyl)glycidicacidmethylester
  • methyl 3-(p-methoxyphenyl)oxirane-2-carboxylate
  • Oxiranecarboxylic acid, 3-(4-methoxyphenyl)-, methyl ester
  • TRANS-2,3-EPOXY-3(4-METHOXYPHENYL)-PROPIONICACIDMETHYLES.
  • METHYL 3-(4-METHOXYPHENYL)OXIRANE-2-CARBOXYLATE
  • 3-(4-Methoxyphenyl)-oxiranecarboxylic acid methyl ester
CAS:
42245-42-1
MF:
C11H12O4
MW:
208.21
EINECS:
255-735-1
Product Categories:
  • API intermediates
  • Epoxide Monomers
  • Monomers
  • Polymer Science
Mol File:
42245-42-1.mol
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Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate Chemical Properties

Melting point:
69-71 °C(lit.)
solubility 
Dichloromethane; Chloroform; Ethyl Acetate; DMSO;
form 
Solid
color 
White
EPA Substance Registry System
Oxiranecarboxylic acid, 3-(4-methoxyphenyl)-, methyl ester (42245-42-1)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3

MSDS

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Methyl 3-(4-methoxyphenyl)oxirane-2-carboxylate Usage And Synthesis

Description

Methyl 2,3 epoXY-3-(4-methoxyphenyl)propionate is an intermediate product in the synthesis of diltiazem hydrochloride. Contact dermatitis was observed in several laboratory technicians.

Uses

Methyl trans-3-(4-Methoxyphenyl)glycidate is an intermediate used in the synthesis of Clentiazem (C573035), which is a benzothiazepine-like calcium antagonists; Enhances endothelium-dependent coronary artery relaxation.

Contact allergens

Methyl 2,3 epoxy-3-(4-methoxyphenyl)propionate is an intermediate product in the synthesis of diltiazem hydrochloride. Contact dermatitis was observed in several laboratory technicians.

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