HUMAN MIP-1BETA
HUMAN MIP-1BETA Basic information
- Product Name:
- HUMAN MIP-1BETA
- Synonyms:
-
- RHMIP-1BETA
- REC MIP-1BETA (HUMAN)
- REC MIP-1B (HUMAN)
- MACROPHAGE INFLAMMATORY PROTEIN, BETA-1, HUMAN
- MACROPHAGE INFLAMMATORY PROTEIN-1 BETA
- MACROPHAGE INFLAMMATORY PROTEIN-1BETA, HUMAN
- MACROPHAGE INFLAMMATORY PROTEIN-1BETA, HUMAN, RECOMBINANT
- MACROPHAGE INFLAMMATORY PROTEIN-1BETA, HUMAN, RECOMBINANT, SPODOPTERA FRUGIPERDA
- MW:
- 0
- Mol File:
- Mol File
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HUMAN MIP-1BETA Chemical Properties
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- human
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Safety Information
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 26-36/37/39-45
MSDS
- Language:English Provider:SigmaAldrich
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HUMAN MIP-1BETA Usage And Synthesis
Biological Activity
MIP-1β (macrophage inflammatory protein-1β), or CCL4L1 (C-C motif chemokine ligand 4 like 1), interacts with its major G protein-coupled receptors CCR5 and CCR8, and promotes the migration of immune cells, such as monocytes, natural killer (NK) cells, and T cells, maturation of dendritic cells (DCs), T cell and granulocyte activation, and T cell differentiation. It is an age associated inflammatory cytokine, and it shows elevated expression in the monocytes and blood of elderly individuals. MIP-1β plays a wide role in immune responses, and hence, its expression is tightly controlled during T-cell differentiation and activation.