GERMACRONE
GERMACRONE Basic information
- Product Name:
- GERMACRONE
- Synonyms:
-
- 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3Z,7E)-
- CAS:
- 32663-51-7
- MF:
- C15H22O
- MW:
- 218.33
- Mol File:
- Mol File
More
Less
GERMACRONE Chemical Properties
- Boiling point:
- 330.3±42.0 °C(Predicted)
- Density
- 0.916±0.06 g/cm3(Predicted)
More
Less
GERMACRONE Usage And Synthesis
Uses
cis,trans-Germacrone is a isomer of Germacrone (HY-N0440). Germacrone exhibits a wide range of antitumor, antioxidant and anti-inflammatory effects. Germacrone inhibits lung cancer cell proliferation and alters the Akt/MDM2/p53. Germacrone also arrests cell cycle at G1/S phase[1].
References
[1] Zhao Y, et al. Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway. Mol Med Rep. 2021 Jun;23(6):452. DOI:10.3892/mmr.2021.12091