(±)-4-aminohex-5-enoic acid
(±)-4-aminohex-5-enoic acid Basic information
- Product Name:
- (±)-4-aminohex-5-enoic acid
- Synonyms:
-
- (±)-4-aminohex-5-enoic acid
- CPP 109
- 5-Hexenoic acid, 4-amino-
- SABRIL; Γ-VINYL-GABA
- rac-VigabatrinDiscontinued See V253010
- (+/-)-Vigabatrin
- Vigabatrin, racemic mixture
- Vigabatrin hydrochloride salt, racemic mixture
- CAS:
- 68506-86-5
- MF:
- C6H11NO2
- MW:
- 129.16
- EINECS:
- 270-929-6
- Mol File:
- 68506-86-5.mol
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(±)-4-aminohex-5-enoic acid Chemical Properties
- Melting point:
- 209℃
- Boiling point:
- 277.7±28.0 °C(Predicted)
- Density
- 1.064±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Methanol (Slightly), Water (Slightly)
- pka
- 4.36±0.10(Predicted)
- form
- Solid
- color
- Off-White
- Water Solubility
- Soluble to 100 mM in water
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Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- MP7745000
- HS Code
- 2922498050
- Hazardous Substances Data
- 68506-86-5(Hazardous Substances Data)
- Toxicity
- LD50 oral in rat: 3gm/kg
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(±)-4-aminohex-5-enoic acid Usage And Synthesis
Uses
rac-Vigabatrin a novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.
Definition
ChEBI: Vigabatrin is a gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase It has a role as an anticonvulsant and an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor.
Biochem/physiol Actions
Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.
storage
Store at +4°C
(±)-4-aminohex-5-enoic acidSupplier
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