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(±)-4-aminohex-5-enoic acid

Product Name
(±)-4-aminohex-5-enoic acid
CAS No.
68506-86-5
Chemical Name
(±)-4-aminohex-5-enoic acid
Synonyms
CPP 109;(±)-Vigabatrin;rac-Vigabatrin;(+/-)-Vigabatrin;Vigabatrin (1712001);SABRIL; Γ-VINYL-GABA;5-Hexenoic acid, 4-amino-;13C,D5-rac-Vigabatrin HCL;()-4-aminohex-5-enoic acid;(±)-4-aminohex-5-enoic acid
CBNumber
CB3877472
Molecular Formula
C6H11NO2
Formula Weight
129.16
MOL File
68506-86-5.mol
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(±)-4-aminohex-5-enoic acid Property

Melting point:
209℃
Boiling point:
277.7±28.0 °C(Predicted)
Density 
1.064±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
pka
4.36±0.10(Predicted)
form 
Solid
color 
Off-White
Water Solubility 
Soluble to 100 mM in water
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
MP7745000
HS Code 
2922498050
Hazardous Substances Data
68506-86-5(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 3gm/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001400
Product name
Vigabatrin
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
10 mg
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
V8261
Product name
(±)-Vigabatrin
Packaging
10mg
Price
$120
Updated
2025/07/31
Sigma-Aldrich
Product number
V8261
Product name
(±)-Vigabatrin
Packaging
50mg
Price
$464.55
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR3429
Product name
Vigabatrin
Purity
certified reference material, pharmaceutical secondary standard
Packaging
400MG
Price
$339
Updated
2025/07/31
Sigma-Aldrich
Product number
5.05989
Product name
Vigabatrin - CAS 68506-86-5 - Calbiochem
Packaging
10MG
Price
$93.5
Updated
2025/07/31
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(±)-4-aminohex-5-enoic acid Chemical Properties,Usage,Production

Uses

rac-Vigabatrin a novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.

Definition

ChEBI: Vigabatrin is a gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase It has a role as an anticonvulsant and an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor.

Biochem/physiol Actions

Irreversible GABA transaminase inhibitor. Increases intracellular concentration of GABA in nerve endings; possesses antiepileptic activity.

in vivo

A significant increase in seizure threshold is observed following systemic (i.p.) administration of high (600 or 1200 mg/kg) doses of Vigabatrin. Bilateral microinjection of Vigabatrin (10 μg) into either the anterior or posterior substantia nigra pars reticulata (SNr) also increased seizure threshold, but less markedly than systemic treatment. Focal delivery into the subthalamic nucleus (STN) increased seizure threshold more markedly than either intranigral or systemic administration of Vigabatrin[1].

storage

Store at +4°C

(±)-4-aminohex-5-enoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(±)-4-aminohex-5-enoic acid Suppliers

Xi’an Caijing Opto-Electrical Science and Technology Co.,Ltd
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029-88294447 029-88292246 029-88296135
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029-88292246
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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MedChemexpress LLC
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021-58955995
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sales@medchemexpress.cn
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Shanghai Balmxy Pharmaceutical Co., Ltd
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Hangzhou J&H Chemical Co., Ltd.
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025-66028182 18626450290
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Sigma-Aldrich
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SPIRO PHARMA
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Codow Chemical Co.,Ltd.
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18620099427
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Guangzhou QiYun Biotechnology Co., Ltd.
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China
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68506-86-5, (±)-4-aminohex-5-enoic acidRelated Search:


  • (±)-4-aminohex-5-enoic acid
  • CPP 109
  • 5-Hexenoic acid, 4-amino-
  • SABRIL; Γ-VINYL-GABA
  • rac-VigabatrinDiscontinued See V253010
  • (+/-)-Vigabatrin
  • Vigabatrin, racemic mixture
  • Vigabatrin hydrochloride salt, racemic mixture
  • Vigabatrin (1712001)
  • rac-Vigabatrin
  • (±)-Vigabatrin
  • ()-4-aminohex-5-enoic acid
  • (±)-4-aminohex-5-enoic acid
  • γ-Vinyl-GABA (4-Aminohexenoic acid) 97%min
  • Neuroepileptics in serum, lyophilized - TDMB 2/11-B SE
  • 13C,D5-rac-Vigabatrin HCL
  • 68506-86-5