Basic information Safety Supplier Related

1-chloro-3-(1-naphthyloxy)propan-2-ol

Basic information Safety Supplier Related

1-chloro-3-(1-naphthyloxy)propan-2-ol Basic information

Product Name:
1-chloro-3-(1-naphthyloxy)propan-2-ol
Synonyms:
  • 1-chloro-3-(1-naphthyloxy)propan-2-ol
  • 1-(Naphth-1-yloxy)-3-chloro-propan-2-ol
  • 1-(1-Naphtyloxy)-3-chloro-2-propanol
  • 1-Chloro-3-(1-naphtyloxy)-2-propanol
  • 1-Chloro-3-(1-naphtyloxy)propane-2-ol
  • 3-Chloro-1-(1-naphtyloxy)-2-propanol
  • Propranolol Impurity 3
  • 1-Chloro-3-(1-naphthoxy)-2-propanol
CAS:
20133-93-1
MF:
C13H13ClO2
MW:
236.69
EINECS:
243-538-3
Mol File:
20133-93-1.mol
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1-chloro-3-(1-naphthyloxy)propan-2-ol Chemical Properties

Boiling point:
158 °C(Press: 0.1 Torr)
Density 
1.246±0.06 g/cm3(Predicted)
pka
13.07±0.20(Predicted)
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1-chloro-3-(1-naphthyloxy)propan-2-ol Usage And Synthesis

Uses

1-Chloro-3-(1-naphthyloxy)-2-propanol is an intermediates in the synthesis of β-adrenergic blocking agents and antihypertensive drugs such as propranolol and nadoxolol. Also used in the kinetic resolution studies of (±)-1-chloro-3-(1-naphthyloxy)-2-propanol in nonaqueous media using lipase-catalyzed esterification.

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