Basic information Safety Supplier Related

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Basic information Safety Supplier Related

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Basic information

Product Name:
MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
Synonyms:
  • N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE
  • methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone
  • N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE
  • MEOSUC-APPV-CMK
  • MEOSUC-AAPV-CMK
  • MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
  • MEOSUC-ALA-ALA-PRO-VAL-CMK
  • ELASTASE INHIBITOR III
CAS:
65144-34-5
MF:
C22H35ClN4O7
MW:
502.99
Product Categories:
  • ProteaseInhibitors
Mol File:
65144-34-5.mol
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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties

Melting point:
159-161 °C
Boiling point:
809.4±65.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
ethanol: 50 mg/mL, clear, colorless
pka
13.05±0.20(Predicted)
form 
Solid
Sensitive 
Moisture Sensitive
BRN 
6167019
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10

MSDS

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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Usage And Synthesis

Uses

A potent irreversible inhibitor of human leukocyte elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONESupplier

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