MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

Product Name: MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
CAS No.: 65144-34-5
Chemical Name: MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE
Synonyms: SPCK;HLE INHIBITOR;MEOSUC-AAPV-CMK;MEOSUC-APPV-CMK;ELASTASE INHIBITOR III;Elastase Inhibitor, SPCK;MEOSUC-ALA-ALA-PRO-VAL-CMK;N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&;MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE;methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone
CBNumber: CB4111744
Molecular Formula: C22H35ClN4O7
Formula Weight: 502.99
MOL File: 65144-34-5.mol

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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Property

Melting point:: 159-161 °C
Boiling point:: 809.4±65.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: ethanol: 50 mg/mL, clear, colorless
pka: 13.05±0.20(Predicted)
form: Solid
Sensitive: Moisture Sensitive
BRN: 6167019

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 5mg
Price: $170
Updated: 2024/03/01

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 10mg
Price: $291
Updated: 2024/03/01

Sigma-Aldrich

Product number: 324745
Product name: Elastase Inhibitor III
Purity: The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
Packaging: 5MG
Price: $238
Updated: 2023/06/20

Alfa Aesar

Product number: J65894
Product name: Elastase Inhibitor III
Packaging: 5mg
Price: $123
Updated: 2021/12/16

Sigma-Aldrich

Product number: M0398
Product name: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone
Purity: elastase inhibitor
Packaging: 25mg
Price: $549
Updated: 2024/03/01

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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Chemical Properties,Usage,Production

Uses

A potent irreversible inhibitor of human leukocyte elastase

Definition

ChEBI: A tripeptide derived from methoxysuccinyl-Ala-Ala-Pro-Val by conversion of the terminal carboxy group to the corresponding chloromethyl ketone.

General Description

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

Biochem/physiol Actions

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

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MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE Suppliers

China 54 Germany 1 Switzerland 1 United Kingdom 2 United States 11 Global 69

GL Biochem (Shanghai) Ltd

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VDM Biochemicals

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Sigma-Aldrich

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Shanghai Chaolan Chemical Technology Center

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Hangzhou Peptidego Biotech Co.,Ltd.

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Nanjing TGpeptide Biotechnology Co.,Ltd.

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65144-34-5, MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONERelated Search:

Elastase 2-AMINO-1-PYRROLIDIN-1-YL-ETHANONE HCL N,N-DIETHYL-2-(METHYLAMINO)ACETAMIDE HYDROCHLORIDE N-ME-GLY-NME2 1-ACETAMIDO-ACETONE MEOSUC-ALA-ALA-PRO-ALA-CHLOROMETHYLKETONE H-ALA-PRO-NH2 HCL Methyl 4-aminobutyrate hydrochloride H-ALA-ALA-ALA-NH2 HCL 2-AMINO-N,N-DIETHYL-ACETAMIDE HCL N-(1-methyl-2-oxopropyl)acetamide ALA-ALA-PRO-VAL-CMK H-PRO-NHET HCL 2-METHYLAMINO-1-PYRROLIDIN-1-YL-ETHANONE X HCL >98% MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

N-(METHOXYSUCCINYL)-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE CHLOROMETHYLKETONE

methoxysuccinyl-alanyl-alanyl-prolyl-valinechloromethylketone

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYL KETONE

MEOSUC-APPV-CMK

MEOSUC-AAPV-CMK

MEOSUC-ALA-ALA-PRO-VAL-CHLOROMETHYLKETONE

MEOSUC-ALA-ALA-PRO-VAL-CMK

ELASTASE INHIBITOR III

HLE INHIBITOR

N-(methoxysuccinyl)-L-ala-L-ala-L-prol.-L-val-chlorome.ket.

N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL*CHLORO METHYL KETO

N-(METHOXYSUCCINYL)-L-ALA-L-ALA-L-PROL.&

N(methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine CMK

SPCK

Elastase Inhibitor, SPCK

methoxysuccinyl-Ala-Ala-Pro-Val chloromethyl ketone

methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(3S)-1-chloro-4-methyl-2-oxopentan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate

L-Prolinamide, N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-N-[(1S)-3-chloro-1-(1-methylethyl)-2-oxopropyl]-

65144-34-5

C22H35ClN4O7

C22H35N4O7Cl

Biochemicals and Reagents

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Metalloproteinase Inhibitors

Cytoskeleton and Extracellular Matrix

Enzyme Inhibitors

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Extracellular Matrix

Substrate Analogs

ProteaseInhibitors