S-(2,4-Dinitrophenyl)-Glutathione Chemical Properties

Melting point:

210-212° dec.

Boiling point:

895.1±65.0 °C(Predicted)

Density 

1.61±0.1 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Water: Slightly Soluble

form 

A solid

pka

2.21±0.10(Predicted)

S-(2,4-Dinitrophenyl)-Glutathione Usage And Synthesis

Description

S-(2,4-Dinitrophenyl)-glutathione is a substrate for glutathione-S-transferase with a kinetic dissociation constant of 7 μM. In vitro, it is transported by multidrug resistance protein 1 (MDR1) and MDR3, which are transporters that confer resistance to some chemotherapeutics.

Chemical Properties

Light Yellow Solid

Uses

A substrate for Glutathione-S-Transferase, with a kinetically determined dissociation constant of 7uM.

Definition

ChEBI: A Glu-Cys-Gly tripeptide glutathione conjugate containing a 2,4-dinitrophenyl substituent on the S of Cys.

References

[1] V L SCHRAMM. Kinetic studies and active site-binding properties of glutathione S-transferase using spin-labeled glutathione, a product analogue.[J]. The Journal of Biological Chemistry, 1984, 259 2: 714-722.
[2] H ZENG. Transport of amphipathic anions by human multidrug resistance protein 3.[J]. Cancer research, 2000, 60 17: 4779-4784.

S-(2,4-Dinitrophenyl)-Glutathione(26289-39-4)Related Product Information

• S-(1,2-dichlorovinyl)cysteine
• CloticasonePropionate
• TYROSINASE
• FETAL BOVINE SERUM USA ORIGIN
• Butyrylcholinesterase
• FETAL BOVINE SERUM USA ORIGIN GAMMA
• 6-Mercaptopurine
• Acetylcholine
• S-(2,4-Dinitrophenyl)-Glutathione