S-SULFO-L-CYSTEINE SODIUM SALT Chemical Properties

Melting point:

184-185°C

Density 

1.841±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

H₂O: 20 mg/mL, clear, colorless

pka

-4.49±0.30(Predicted)

form 

Solid

color 

White

BRN 

1726832

Stability:

Store in Freezer at -20°C

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

S-SULFO-L-CYSTEINE SODIUM SALT Usage And Synthesis

Chemical Properties

White Solid

Uses

An amino acid derivative with neuropathological interest. An NMDA receptor ligand

Definition

ChEBI: An S-substituted L-cysteine where the S-substituent is specified as a sulfo group.

Biological Activity

L-Cysteine S-sulfate (LCSS) is used as an NMDA glutamatergic receptor agonist. It serves as a substrate for cystine lyase(s).
Cysteine is one of the functional amino acids th at are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. at physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cysteine serves as a precursor for the rate limiting step in glutathione synthesis th at occurs in neurons. It donates inorganic sulfate for detoxification reactions. Therefore, L-cysteine might be associated with neuroprotection. It is found to obstruct the entry of heavy metal ions across the blood-brain barrier into the brain. Increased levels of L-cysteine might lead to neurotoxicity.

S-SULFO-L-CYSTEINE SODIUM SALT(1637-71-4)Related Product Information

• Acetylcysteine Impurity 3
• LANTHIONINE
• N,S-Carboxymethyl Cysteine
• L-CYSTEINESULFINIC ACID
• Carbocisteine LactaM
• N-Propionyl-L-cysteine
• H-CYS(SO3H)-OH SODIUM SALT
• S-SULFO-L-CYSTEINE SODIUM SALT
• BOC-CYS(SO3H)-OH DISODIUM SALT