(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Basic information
- Product Name:
- (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
- Synonyms:
-
- (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
- B-Cortolone
- (20R)-3α,17α,20,21-Tetrahydroxy-5β-pregnan-11-one
- 2-Cortolone
- 5β-pregnan-3α, 17, 20β, 21-tetrol-11-one
- β-Cortolone
- β-Cortolone D5
- Pregnan-11-one, 3,17,20,21-tetrahydroxy-, (3α,5β,20R)-
- CAS:
- 667-66-3
- MF:
- C21H34O5
- MW:
- 366.495
- Mol File:
- 667-66-3.mol
More
Less
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Chemical Properties
- Melting point:
- 249-258oC
- Boiling point:
- 564.1±50.0 °C(Predicted)
- Density
- 1.248±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly)
- pka
- 13.95±0.70(Predicted)
- form
- Solid
- color
- White to Off-White
More
Less
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one Usage And Synthesis
Uses
β-Cortolone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
Definition
ChEBI: Beta-Cortolone is a 21-hydroxy steroid.
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-oneSupplier
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Wuxi Helen Biotechnology Co., Ltd.,
- Tel
- 0510-85629785 18013409632
- sales@reading-chemicals.com
Shanghai Hewu Biotechnology Co., LTD
- Tel
- 021-57886085 17317861055
- shhebio@126.com
More
Less
(3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one(667-66-3)Related Product Information
- 5B-PREGNANE-3A-17A-20B-TRIOL*CRYSTALLINE
- 5BETA-PREGNAN-3ALPHA, 17ALPHA, 20BETA, 21-TETROL-11-ONE-3BETA-D-GLUCURONIDE-20 21-ACETONIDE
- (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1R)-1,2-dihydroxyethyl]-3,17-dihydr oxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopen ta[a]phenanthren-11-one
- 2-HEPTANONE，5-(HYDROXYMETHYL)
- Menthone
- 5-BETA-PREGNAN-3-ALPHA, 20-BETA-DIOL