bacimethrin
bacimethrin Basic information
- Product Name:
- bacimethrin
- Synonyms:
-
- bacimethrin
- 4-Amino-2-methoxy-5-pyrimidinemethanol
- 4-Amino-2-methoxypyrimidine-5-methanol
- 4-Amino-2-methoxy-5-pyrimidylmethanol
- 4-Amino-5-(hydroxymethyl)-2-methoxypyrimidine
- Bacimethrine
- Bacimetrin
- NSC 66577
- CAS:
- 3690-12-8
- MF:
- C6H9N3O2
- MW:
- 155.15
- Mol File:
- 3690-12-8.mol
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bacimethrin Chemical Properties
- Melting point:
- 174℃ (decomposition) (methanol )
- Boiling point:
- 278.95°C (rough estimate)
- Density
- 1.3092 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C(protect from light)
- pka
- 13.04±0.10(Predicted)
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bacimethrin Usage And Synthesis
Uses
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth[1][2].
References
[1] Natalia S Nemeria, et al. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin. Biochemistry. 2016 Feb 23;55(7):1135-48. DOI:10.1021/acs.biochem.5b01300
[2] J L Zilles, et al. Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. J Bacteriol. 2000 Oct;182(19):5606-10. DOI:10.1128/JB.182.19.5606-5610.2000
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