ERYSOLIN
ERYSOLIN Basic information
- Product Name:
- ERYSOLIN
- Synonyms:
-
- ERYSOLIN
- Erysoline
- 4-(Methanesulfonyl)butyl isothiocyanate
- ERYSOLIN(RG)(PLEASE CALL)
- Butane, 1-isothiocyanato-4-(methylsulfonyl)-
- ACM 504847
- ACM504847
- ACM-504847
- CAS:
- 504-84-7
- MF:
- C6H11NO2S2
- MW:
- 193.29
- Mol File:
- 504-84-7.mol
ERYSOLIN Chemical Properties
- storage temp.
- −20°C
- solubility
- Chloroform: Soluble
Methanol: Soluble
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-42
- Safety Statements
- 26-36/37/39-45
- RIDADR
- 1759
- WGK Germany
- 3
- HazardClass
- 8
- PackingGroup
- III
MSDS
- Language:English Provider:SigmaAldrich
ERYSOLIN Usage And Synthesis
Description
This alkaloid has been found in anum ber of Erythrina species. It forms colourless needles which have a somewhat indefinite melting point, softening over a wide range of temperature. The IS-methyl ether is identical with erythravine (q.v.).
Uses
Erysolin is a chemical shown to increase the amount of daunomycin and vinblastine in PANC-1 cells.
References
[1] Millington, Steinman, Reinhart, J. Arner. Chern. Soc., 96, 1909 (1974)
[2] Hargreaves et al., Lloydia, 37, S69 (1974)
[3] [1] BING-LONG LI . Synthesis and antitumor activity of erysolin and its metabolites[J]. Journal of Asian Natural Products Research, 2023, 25 4: Pages 369-378. DOI: 10.1080/10286020.2022.2091989
[4] [2] NICOLE A. DOUDICAN Seth J O Benjamin Bowling. Enhancement of arsenic trioxide cytotoxicity by dietary isothiocyanates in human leukemic cells via a reactive oxygen species-dependent mechanism[J]. Leukemia research, 2010, 34 2: Pages 229-234. DOI: 10.1016/j.leukres.2009.05.017
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