Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Natural Products >  Flavonoids >  morusin

morusin

Basic information Safety Supplier Related

morusin Basic information

Product Name:
morusin
Synonyms:
  • Moracin
  • 2-(2,4-Dihydroxyphenyl)-3-(3-methyl-2-butenyl)-5-hydroxy-8,8-dimethyl-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
  • 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
  • Mulberrochromene
  • 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8,8-dimethyl-3-(3-methyl-2-buten-1-yl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
  • 4H,8H-Benzo(1,2-B:3,4-B')dipyran-4-one,2-(2,4-dihydroxyphenyl)-5-hydroxy-8,8-diMethyl-3-(3-Methyl-2-butenyl)
  • Morusin(Mulberrochromene)
  • morusin 62596-29-6
CAS:
62596-29-6
MF:
C25H24O6
MW:
420.45
EINECS:
300-006-7
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
62596-29-6.mol
More
Less

morusin Chemical Properties

Melting point:
232-235℃
Boiling point:
656.7±55.0 °C(Predicted)
Density 
1.303
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMF: 20mg/mL; DMF:PBS (pH 7.2) (1:3): 0.25mg/mL; DMSO: 10mg/mL; Ethanol: 15mg/mL
form 
powder
pka
6.55±0.60(Predicted)
color 
Beige-orange
Stability:
Light Sensitive
More
Less

morusin Usage And Synthesis

Chemical Properties

Soluble in DMSO, hot methanol, insoluble in petroleum ether, chloroform. Derived from the root bark of Morous alba L., family Moraceae, with the yellowish brown rough skin removed.

Uses

Morusin is an inhibitor of human cervical cancer stem cell growth, attenuating NF-kB activity, and initiating apoptosis.

Definition

ChEBI: An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8.

in vivo

Morusin retards the growth of breast cancer significantly. Mean tumor weight of the control mice is 1.14±0.30 g, and those of the mice administrated with 5 and 10 mg/kg of morusin are 0.61±0.23 and 0.41±0.10 g, respectively, tumor inhibitory rates are 46.5 %, and 64.1 %, respectively[1].

IC 50

p65; STAT3

morusinSupplier

Chembest Research Laboratories Limited
Tel
+86-21-20908456
Email
sales@BioChemBest.com
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Email
chenyj@titansci.com
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Email
cdhxsj@163.com
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Email
sales@sungening.com
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com
More
Less

morusin(62596-29-6)Related Product Information