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2-ACETAMIDO-5-NITROTHIAZOLE

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2-ACETAMIDO-5-NITROTHIAZOLE Basic information

Product Name:
2-ACETAMIDO-5-NITROTHIAZOLE
Synonyms:
  • AKOS AU36-M376
  • 2-ACETYLAMINO-5-NITROTHIAZOLE
  • 2-ACETAMINO-5-NITROTHIAZOLE
  • 2-ACETAMIDO-5-NITROTHIAZOLE
  • N-(5-NITRO-2-THIAZOLYL)ACETAMIDE
  • 2-acetamido-5-nitro-thiazol
  • 5-Nitro-2-acetamidothiazole
  • 5-Nitro-2-acetilaminotiazolo
CAS:
140-40-9
MF:
C5H5N3O3S
MW:
187.18
EINECS:
205-414-7
Product Categories:
  • CORT SOL
Mol File:
140-40-9.mol
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2-ACETAMIDO-5-NITROTHIAZOLE Chemical Properties

Melting point:
263°C (dec.)
Density 
1.546 (estimate)
refractive index 
1.6560 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMF:3.0(Max Conc. mg/mL);16.03(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);53.43(Max Conc. mM)
form 
solid
pka
8.78±0.50(Predicted)
color 
White to Amber
Merck 
14,410
BRN 
167361
CAS DataBase Reference
140-40-9(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
22-36/37-24/25
RTECS 
XJ1570000
HS Code 
29341000
Toxicity
chicken,LD50,oral,800mg/kg (800mg/kg),Antibiotics and Chemotherapy Vol. 5, Pg. 540, 1955.

MSDS

  • Language:English Provider:ALFA
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2-ACETAMIDO-5-NITROTHIAZOLE Usage And Synthesis

Chemical Properties

Yellow-brown solid

Uses

antiinflammatory, glucocorticoid

Uses

Nithiamide is a drug for chemotherapy. A protistocide drug with antibacterial activity.

Definition

ChEBI: Aminitrozole is an aromatic amide and a member of acetamides.

Safety Profile

Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of SO, and NOx,.

Purification Methods

Recrystallise acinitrazole from EtOH or AcOH. [Hurd & Wehrmeister J Am Chem Soc 71 4007 1949, Beilstein 27 III/IV 4676.]

2-ACETAMIDO-5-NITROTHIAZOLESupplier

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