2-ACETAMIDO-5-NITROTHIAZOLE Chemical Properties

Melting point:

263°C (dec.)

Density 

1.546 (estimate)

refractive index 

1.6560 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMF:3.0(Max Conc. mg/mL);16.03(Max Conc. mM)
DMSO:10.0(Max Conc. mg/mL);53.43(Max Conc. mM)

form 

solid

pka

8.78±0.50(Predicted)

color 

White to Amber

Merck 

14,410

BRN 

167361

CAS DataBase Reference

140-40-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

Safety Statements 

22-36/37-24/25

RTECS 

XJ1570000

HS Code 

29341000

Toxicity

chicken,LD50,oral,800mg/kg (800mg/kg),Antibiotics and Chemotherapy Vol. 5, Pg. 540, 1955.

MSDS

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2-ACETAMIDO-5-NITROTHIAZOLE Usage And Synthesis

Chemical Properties

Yellow-brown solid

Uses

antiinflammatory, glucocorticoid

Uses

Nithiamide is a drug for chemotherapy. A protistocide drug with antibacterial activity.

Definition

ChEBI: Aminitrozole is an aromatic amide and a member of acetamides.

Safety Profile

Poison by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of SO, and NOx,.

Purification Methods

Recrystallise acinitrazole from EtOH or AcOH. [Hurd & Wehrmeister J Am Chem Soc 71 4007 1949, Beilstein 27 III/IV 4676.]

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